Senescent Kidney Cells in Hypertensive Patients Release Urinary Extracellular Vesicles
Background Hypertension may be associated with renal cellular injury. Cells in distress release extracellular vesicles (EVs), and their numbers in urine may reflect renal injury. Cellular senescence, an irreversible growth arrest in response to a noxious milieu, is characterized by release of proinf...
Main Authors: | Adrian Santelli, In O. Sun, Alfonso Eirin, Abdelrhman M. Abumoawad, John R. Woollard, Amir Lerman, Stephen C. Textor, Amrutesh S. Puranik, Lilach O. Lerman |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-06-01
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Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
Subjects: | |
Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.119.012584 |
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