miR-181b targets semaphorin 3A to mediate TGF-β–induced endothelial-mesenchymal transition related to atrial fibrillation
Atrial fibrosis is an essential contributor to atrial fibrillation (AF). It remains unclear whether atrial endocardial endothelial cells (AEECs) that undergo endothelial-mesenchymal transition (EndMT) are among the sources of atrial fibroblasts. We studied human atria, TGF-β–treated human AEECs, car...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical Investigation
2022-07-01
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Series: | The Journal of Clinical Investigation |
Subjects: | |
Online Access: | https://doi.org/10.1172/JCI142548 |