Past, Present, and Future of Rituximab—The World’s First Oncology Monoclonal Antibody Therapy

Rituximab is a chimeric mouse/human monoclonal antibody (mAb) therapy with binding specificity to CD20. It was the first therapeutic antibody approved for oncology patients and was the top-selling oncology drug for nearly a decade with sales reaching $8.58 billion in 2016. Since its initial approval...

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Bibliographic Details
Main Authors: Timothy M. Pierpont, Candice B. Limper, Kristy L. Richards
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00163/full