Cellular delivery of relaxin-2 mRNA as a potential treatment for kidney fibrosis

Renal fibrosis is a pathological feature of chronic kidney disease and its progression correlates with kidney function impairment. Since there are currently no specific therapies for renal fibrosis, we explored whether inducing local production of the anti-fibrotic molecule relaxin-2 in kidney cells...

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Bibliographic Details
Main Authors: Chenguang Ding, Bo Wang, Xiang Feng Lai, Yingcong Guo, Greg Tesch, Xiaoming Ding, Jin Zheng, PuXun Tian, Sharon Ricardo, Hsin-Hui Shen, Wujun Xue
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S259000642300176X