Distinctive profile of monomeric and polymeric anti-SSA/Ro52 immunoglobulin A1 isoforms in saliva of patients with primary Sjögren’s syndrome and Sicca

Objective Primary Sjögren’s syndrome (pSS) is the second most common chronic autoimmune connective tissue disease. Autoantibodies, immunoglobulin (IgG) anti-SSA/Ro, in serum is a key diagnostic feature of pSS. Since pSS is a disease of the salivary gland, we investigated anti-SSA/Ro52 in saliva.Meth...

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Bibliographic Details
Main Authors: Yeong Wook Song, David A Elashoff, Fang Wei, David Chia, David Akin, David T W Wong, Nabihah Tayob, Tristan Grogan, Ju Yeon Kim, Samantha Chiang, Sarah Kamounah, Jin Kyun Park, Anne Marie Lynge Pedersen
Format: Article
Language:English
Published: BMJ Publishing Group 2024-05-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/10/2/e003666.full