Relationship between the thrombospondin-1/Toll-like receptor 4 (TSP1/TLR4) pathway and vitamin D levels in obese and normal weight subjects with different metabolic phenotypes

Relationship between the thrombospondin-1/Toll-like receptor 4 (TSP1/TLR4) pathway and vitamin D levels in obese and normal weight subjects with different metabolic phenotypes

Abstract Thrombospondin-1 (TSP1) contributes to obesity-associated inflammation via activating Toll-like receptor 4 (TLR4). The regulatory role of vitamin D on this pathway has been suggested. This study aimed to investigate the relationship between TSP1/TLR4 pathway and vitamin D in obese and norma...

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Bibliographic Details
Main Authors: Eman Y. Khairy, Azza Saad
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Physiological Sciences
Subjects:
Vitamin D
Thrombospondin-1
Toll-like receptor 4
Metabolic phenotypes
Inflammation
Metabolic dysfunction
Online Access:https://doi.org/10.1186/s12576-023-00887-z

Internet

https://doi.org/10.1186/s12576-023-00887-z

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