Zoledronic acid and atorvastatin inhibit αvβ3-mediated adhesion of breast cancer cells

Bone metastases represent common long term complications of patients with breast cancer. Zoledronic acid, an amino-bisphosphonate and mevalonate pathway inhibitor, is an established agent for the treatment of bone metastases. Direct antitumor effects of zoledronic acid have been proposed in breast c...

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Bibliographic Details
Main Authors: Maria Wilke, Andy Göbel, Martina Rauner, Peggy Benad-Mehner, Norbert Schütze, Susanne Füssel, Peyman Hadji, Lorenz C. Hofbauer, Tilman D. Rachner
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Journal of Bone Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137414000037