Pubertal attainment and Leydig cell function following pediatric hematopoietic stem cell transplantation: a three-decade longitudinal assessment

Pubertal attainment and Leydig cell function following pediatric hematopoietic stem cell transplantation: a three-decade longitudinal assessment

IntroductionImpaired testosterone secretion is a frequent sequela following hematopoietic stem cell transplantation (HSCT) in pediatrics, but long-term longitudinal trendlines of clinical and biochemical findings are still scanty.MethodsMonocentric, retrospective analysis. Male patients transplanted...

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Main Authors: Alessandro Cattoni, Maria Laura Nicolosi, Giulia Capitoli, Alberto Gadda, Silvia Molinari, Sotiris Louka, Andrea Buonsante, Simona Orlandi, Gianluca Salierno, Iacopo Bellani, Francesca Vendemini, Giorgio Ottaviano, Alberto Gaiero, Graziella Fichera, Andrea Biondi, Adriana Balduzzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Endocrinology
Subjects:
treosulfan
busulfan
total body irradiation
hypogonadism
gonadal disorders
hematopoietic stem cell transplantation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1292683/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1292683/full

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