A New Generation of IMiDs as Treatments for Neuroinflammatory and Neurodegenerative Disorders

A New Generation of IMiDs as Treatments for Neuroinflammatory and Neurodegenerative Disorders

The immunomodulatory imide drug (IMiD) class, which includes the founding drug member thalidomide and later generation drugs, lenalidomide and pomalidomide, has dramatically improved the clinical treatment of specific cancers, such as multiple myeloma, and it combines potent anticancer and anti-infl...

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Bibliographic Details
Main Authors: Katherine O. Kopp, Margaret E. Greer, Elliot J. Glotfelty, Shih-Chang Hsueh, David Tweedie, Dong Seok Kim, Marcella Reale, Neil Vargesson, Nigel H. Greig
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomolecules
Subjects:
immunomodulatory imide drugs (IMiDs)
thalidomide
pomalidomide
neuroinflammation
cereblon
traumatic brain injury
Online Access:https://www.mdpi.com/2218-273X/13/5/747

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https://www.mdpi.com/2218-273X/13/5/747

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