β‑aminoisobutyric acid ameliorates hypertensive vascular remodeling via activating the AMPK/SIRT1 pathway in VSMCs

β‑aminoisobutyric acid ameliorates hypertensive vascular remodeling via activating the AMPK/SIRT1 pathway in VSMCs

ABSTRACTExcessive proliferation and migration of vascular smooth muscle cells (VSMCs) play a fundamental role in the pathogenesis of hypertension-related vascular remodeling. β-aminoisobutyric acid (BAIBA) is a nonprotein β-amino acid with multiple pharmacological actions. Recently, BAIBA has been s...

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Bibliographic Details
Main Authors: Bo Yin, Yu-Bin Wang, Xiang Li, Xu-Wei Hou
Format: Article
Language:English
Published: Taylor & Francis Group 2022-06-01
Series:Bioengineered
Subjects:
Hypertension
vascular smooth muscle cells
vascular remodeling
β-aminoisobutyric acid
oxidative stress
Online Access:https://www.tandfonline.com/doi/10.1080/21655979.2022.2085583

Internet

https://www.tandfonline.com/doi/10.1080/21655979.2022.2085583

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