The Road Not Taken with Pyrrole-Imidazole Polyamides: Off-Target Effects and Genomic Binding
The high sequence specificity of minor groove-binding <i>N</i>-methylpyrrole-<i>N</i>-methylimidazole polyamides have made significant advances in cancer and disease biology, yet there have been few comprehensive reports on their off-target effects, most likely as a consequen...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-04-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/10/4/544 |