Myasthenia gravis complement activity is independent of autoantibody titer and disease severity.

Acetylcholine receptor (AChR) autoantibodies, found in patients with autoimmune myasthenia gravis (MG), can directly contribute to disease pathology through activation of the classical complement pathway. Activation of the complement pathway in autoimmune diseases can lead to a secondary complement...

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Bibliographic Details
Main Authors: Miriam L Fichtner, Michelle D Hoarty, Douangsone D Vadysirisack, Bailey Munro-Sheldon, Richard J Nowak, Kevin C O'Connor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0264489