Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data.

Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data.

Broadly neutralizing monoclonal antibodies effective against the majority of circulating isolates of HIV-1 have been isolated from a small number of infected individuals. Definition of the conformational epitopes on the HIV spike to which these antibodies bind is of great value in defining targets f...

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Bibliographic Details
Main Authors: Andrew L Ferguson, Emilia Falkowska, Laura M Walker, Michael S Seaman, Dennis R Burton, Arup K Chakraborty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24312481/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24312481/?tool=EBI

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