FBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis

Abstract Oncogene Moesin plays critical role in initiation, progression, and metastasis of multiple cancers. It exerts oncogenic activity due to its high-level expression as well as posttranslational modification in cancer. However, factors responsible for its high-level expression remain elusive. I...

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Bibliographic Details
Main Authors: Ganesh Kumar Barik, Osheen Sahay, Anindya Mukhopadhyay, Rajesh Kumar Manne, Sehbanul Islam, Anup Roy, Somsubhra Nath, Manas Kumar Santra
Format: Article
Language:English
Published: Nature Publishing Group 2023-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06127-x