Nanoparticles Synergize Ferroptosis and Cuproptosis to Potentiate Cancer Immunotherapy

Abstract The recent discovery of copper‐mediated and mitochondrion‐dependent cuproptosis has aroused strong interest in harnessing this novel mechanism of cell death for cancer therapy. Here the design of a core‐shell nanoparticle, CuP/Er, for the co‐delivery of copper (Cu) and erastin (Er) to cance...

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Bibliographic Details
Main Authors: Youyou Li, Jing Liu, Yimei Chen, Ralph R. Weichselbaum, Wenbin Lin
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202310309