A systems biology model of junctional localization and downstream signaling of the Ang–Tie signaling pathway
Abstract The Ang–Tie signaling pathway is an important vascular signaling pathway regulating vascular growth and stability. Dysregulation in the pathway is associated with vascular dysfunction and numerous diseases that involve abnormal vascular permeability and endothelial cell inflammation. The un...
Main Authors: | Yu Zhang, Christopher D. Kontos, Brian H. Annex, Aleksander S. Popel |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-08-01
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Series: | npj Systems Biology and Applications |
Online Access: | https://doi.org/10.1038/s41540-021-00194-6 |
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