New Guanidine Alkaloids Batzelladines O and P from the Marine Sponge <i>Monanchora pulchra</i> Induce Apoptosis and Autophagy in Prostate Cancer Cells

New Guanidine Alkaloids Batzelladines O and P from the Marine Sponge <i>Monanchora pulchra</i> Induce Apoptosis and Autophagy in Prostate Cancer Cells

Two new guanidine alkaloids, batzelladines O (<b>1</b>) and P (<b>2</b>), were isolated from the deep-water marine sponge <i>Monanchora pulchra.</i> The structures of these metabolites were determined by NMR spectroscopy, mass spectrometry, and ECD. The isolated c...

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Bibliographic Details
Main Authors: Sergey A. Dyshlovoy, Larisa K. Shubina, Tatyana N. Makarieva, Alla G. Guzii, Jessica Hauschild, Nadja Strewinsky, Dmitrii V. Berdyshev, Ekaterina K. Kudryashova, Alexander S. Menshov, Roman S. Popov, Pavel S. Dmitrenok, Markus Graefen, Carsten Bokemeyer, Gunhild von Amsberg
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Marine Drugs
Subjects:
batzelladines
sponge
<i>Monanchora pulchra</i>
anticancer activity
prostate cancer
apoptosis
Online Access:https://www.mdpi.com/1660-3397/20/12/738

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https://www.mdpi.com/1660-3397/20/12/738

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