Oral hormone pregnancy tests and the risks of congenital malformations: a systematic review and meta-analysis [version 1; referees: 2 approved]

Background: Oral hormone pregnancy tests (HPTs), such as Primodos, containing ethinylestradiol and high doses of norethisterone, were given to over a million women from 1958 to 1978, when Primodos was withdrawn from the market because of concerns about possible teratogenicity. We aimed to study the...

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Bibliographic Details
Main Authors: Carl Heneghan, Jeffrey K. Aronson, Elizabeth Spencer, Bennett Holman, Kamal R. Mahtani, Rafael Perera, Igho Onakpoya
Format: Article
Language:English
Published: F1000 Research Ltd 2018-10-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-1725/v1