Human amniotic mesenchymal stromal cell-derived exosomes promote neuronal function by inhibiting excessive apoptosis in a hypoxia/ischemia-induced cerebral palsy model: A preclinical study

Human amniotic mesenchymal stromal cell-derived exosomes promote neuronal function by inhibiting excessive apoptosis in a hypoxia/ischemia-induced cerebral palsy model: A preclinical study

Background: Cerebral palsy (CP) is a condition resulting from perinatal brain injury and can lead to physical disabilities. Exosomes derived from human amniotic mesenchymal stromal cells (hAMSC-Exos) hold promise as potential therapeutic options. Objective: This study aimed to investigate the impact...

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Bibliographic Details
Main Authors: Yu Zhou, Lu-Na He, Li-Na Wang, Kai-Yun Chen, Shi-Da Qian, Xu-Huan Li, Jing Zang, Dong-Ming Wang, Xue-feng Yu, Jing Gao
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Human amniotic mesenchymal stromal cells
Exosomes
Cerebral palsy
Apoptosis
Stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224002026

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http://www.sciencedirect.com/science/article/pii/S0753332224002026

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