STEAP4 expression in CNS resident cells promotes Th17 cell-induced autoimmune encephalomyelitis
Abstract Background Multiple sclerosis (MS) is a debilitating neurological disease caused by autoimmune destruction of the myelin sheath. Experimental autoimmune encephalomyelitis (EAE) is a widely used animal model for the pathogenesis of MS. We and others have previously demonstrated that IL-17 is...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12974-021-02146-7 |