Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans

Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans

Neutrophils are well-recognized for their pathogen killing mechanisms and disorders of neutrophil count and function are associated with recurrent infections. The Duffy Antigen Receptor for Chemokines (DARC)-null genotype is predominant in sub-Saharan African ancestry populations and is the major ge...

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Bibliographic Details
Main Authors: Kewreshini K. Naidoo, Ayanda Ngubane, Pedzisai Gaza, Amber Moodley, Thumbi Ndung'u, Christina F. Thobakgale
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
neutrophil
function
DARC
duffy
HIV-1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00551/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00551/full

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