Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets.

Transmission of highly pathogenic avian H5N1 viruses from poultry to humans have raised fears of an impending influenza pandemic. Concerted efforts are underway to prepare effective vaccines and therapies including polyclonal or monoclonal antibodies against H5N1. Current efforts are hampered by the...

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Bibliographic Details
Main Authors: Surender Khurana, Amorsolo L Suguitan, Yonaira Rivera, Cameron P Simmons, Antonio Lanzavecchia, Federica Sallusto, Jody Manischewitz, Lisa R King, Kanta Subbarao, Hana Golding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC2661249?pdf=render