Optogenetic targeting of AII amacrine cells restores retinal computations performed by the inner retina

Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to severe visual impairment. Optogenetic reactivation of inner retinal neurons is a promising avenue to restore vision in retinas having lost their photoreceptors. Expression of optogenetic proteins in sur...

Полное описание

Библиографические подробности
Главные авторы: Hanen Khabou, Elaine Orendorff, Francesco Trapani, Marco Rucli, Melissa Desrosiers, Pierre Yger, Deniz Dalkara, Olivier Marre
Формат: Статья
Язык:English
Опубликовано: Elsevier 2023-12-01
Серии:Molecular Therapy: Methods & Clinical Development
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Online-ссылка:http://www.sciencedirect.com/science/article/pii/S2329050123001407