Optogenetic targeting of AII amacrine cells restores retinal computations performed by the inner retina

Optogenetic targeting of AII amacrine cells restores retinal computations performed by the inner retina

Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to severe visual impairment. Optogenetic reactivation of inner retinal neurons is a promising avenue to restore vision in retinas having lost their photoreceptors. Expression of optogenetic proteins in sur...

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Bibliographic Details
Main Authors: Hanen Khabou, Elaine Orendorff, Francesco Trapani, Marco Rucli, Melissa Desrosiers, Pierre Yger, Deniz Dalkara, Olivier Marre
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
vision restoration
retina
optogenetics
gene therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050123001407

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http://www.sciencedirect.com/science/article/pii/S2329050123001407

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