Discovery of Novel Quinazoline Derivatives as Potent Antitumor Agents

In this work, we designed and synthesized a novel series of quinazoline derivatives <b>6</b>–<b>19</b> and then evaluated their broad-spectrum antitumor activity against MGC-803, MCF-7, PC-9, A549, and H1975, respectively. Most of them demonstrated low micromolar cytotoxicity...

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Autors principals: Zhenxi Niu, Shuli Ma, Lei Zhang, Qibing Liu, Shengnan Zhang
Format: Article
Idioma:English
Publicat: MDPI AG 2022-06-01
Col·lecció:Molecules
Matèries:
Accés en línia:https://www.mdpi.com/1420-3049/27/12/3906