Ribosomal profiling of human endogenous retroviruses in healthy tissues

Ribosomal profiling of human endogenous retroviruses in healthy tissues

Abstract Human endogenous retroviruses (HERVs) are the germline embedded proviral fragments of ancient retroviral infections that make up roughly 8% of the human genome. Our understanding of HERVs in physiology primarily surrounds their non-coding functions, while their protein coding capacity remai...

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Bibliographic Details
Main Authors: Nicholas Dopkins, Bhavya Singh, Stephanie Michael, Panpan Zhang, Jez L. Marston, Tongyi Fei, Manvendra Singh, Cedric Feschotte, Nicholas Collins, Matthew L. Bendall, Douglas F. Nixon
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Genomics
Subjects:
Human endogenous retrovirus (HERV)
Ribosomal profiling (RiboSeq)
Protein translation
Dark genome
Endoretrotranslatome (ERT)
Online Access:https://doi.org/10.1186/s12864-023-09909-x

Internet

https://doi.org/10.1186/s12864-023-09909-x

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