Surface plasmon resonance biosensor for exosome detection based on reformative tyramine signal amplification activated by molecular aptamer beacon

Abstract Human epidermal growth factor receptor 2 (HER2)-positive exosomes play an extremely important role in the diagnosis and treatment options of breast cancers. Herein, based on the reformative tyramine signal amplification (TSA) enabled by molecular aptamer beacon (MAB) conversion, a label-fre...

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Bibliographic Details
Main Authors: Wenqin Chen, Zhiyang Li, Wenqian Cheng, Tao Wu, Jia Li, Xinyu Li, Lin Liu, Huijie Bai, Shijia Ding, Xinmin Li, Xiaolin Yu
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-021-01210-x