FOXO transcriptional activity is associated with response to chemoradiation in EAC

FOXO transcriptional activity is associated with response to chemoradiation in EAC

Abstract In this study we aimed to investigate signaling pathways that drive therapy resistance in esophageal adenocarcinoma (EAC). Paraffin-embedded material was analyzed in two patient cohorts: (i) 236 EAC patients with a primary tumor biopsy and corresponding post neoadjuvant chemoradiotherapy (n...

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Bibliographic Details
Main Authors: A. Creemers, A. P. van der Zalm, A. van de Stolpe, L. Holtzer, M. Stoffels, G. K. J. Hooijer, E. A. Ebbing, H. van Ooijen, A. G. C. van Brussel, E. M. G. Aussems-Custers, M. I. van Berge Henegouwen, M. C. C. M. Hulshof, J. J. G. H. M. Bergman, S. L. Meijer, M. F. Bijlsma, H. W. M. van Laarhoven
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Journal of Translational Medicine
Subjects:
Esophageal adenocarcinoma
Pathway analysis
Predictive
Neoadjuvant chemoradiation therapy
Online Access:https://doi.org/10.1186/s12967-022-03376-w

Internet

https://doi.org/10.1186/s12967-022-03376-w

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