Improved isolation of extracellular vesicles by removal of both free proteins and lipoproteins

Improved isolation of extracellular vesicles by removal of both free proteins and lipoproteins

Extracellular vesicles (EVs) are released by all cells into biofluids such as plasma. The separation of EVs from highly abundant free proteins and similarly sized lipoproteins remains technically challenging. We developed a digital ELISA assay based on Single Molecule Array (Simoa) technology for Ap...

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Bibliographic Details
Main Authors: Dmitry Ter-Ovanesyan, Tal Gilboa, Bogdan Budnik, Adele Nikitina, Sara Whiteman, Roey Lazarovits, Wendy Trieu, David Kalish, George M Church, David R Walt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-05-01
Series:eLife
Subjects:
extracellular vesicles
EVs
lipoproteins
ApoB-100
exosomes
Online Access:https://elifesciences.org/articles/86394

Internet

https://elifesciences.org/articles/86394

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