High coverage of targeted lipidomics revealed lipid changes in the follicular fluid of patients with insulin-resistant polycystic ovary syndrome and a positive correlation between plasmalogens and oocyte quality

High coverage of targeted lipidomics revealed lipid changes in the follicular fluid of patients with insulin-resistant polycystic ovary syndrome and a positive correlation between plasmalogens and oocyte quality

BackgroundPolycystic ovary syndrome with insulin resistance (PCOS-IR) is the most common endocrine and metabolic disease in women of reproductive age, and low fertility in PCOS patients may be associated with oocyte quality; however, the molecular mechanism through which PCOS-IR affects oocyte quali...

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Bibliographic Details
Main Authors: Meizi Zhang, Yuanyuan Wang, Jianyong Di, Xuanlin Zhang, Ye Liu, Yixin Zhang, Bowen Li, Simeng Qi, Xiaomin Cao, Li Liu, Shouzeng Liu, Fengqin Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Endocrinology
Subjects:
polycystic ovary syndrome
follicular fluid
lipidomics
oocyte quality
plasmalogens
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1414289/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2024.1414289/full

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