Increased BMSC exosomal miR-140-3p alleviates bone degradation and promotes bone restoration by targeting Plxnb1 in diabetic rats
Abstract Background Diabetes mellitus (DM) is considered to be an important factor for bone degeneration disorders such as bone defect nonunion, which is characterized by physical disability and tremendous economy cost to families and society. Exosomal miRNAs of BMSCs have been reported to participa...
Main Authors: | Ning Wang, Xuanchen Liu, Zhen Tang, Xinghui Wei, Hui Dong, Yichao Liu, Hao Wu, Zhigang Wu, Xiaokang Li, Xue Ma, Zheng Guo |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2022-03-01
|
Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12951-022-01267-2 |
Similar Items
-
Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary
by: Serena Brundu, et al.
Published: (2023-03-01) -
Exosomal miR-140-5p inhibits osteogenesis by targeting IGF1R and regulating the mTOR pathway in ossification of the posterior longitudinal ligament
by: Yifan Tang, et al.
Published: (2022-10-01) -
BMSC exosome-enriched acellular fish scale scaffolds promote bone regeneration
by: Yangyufan Wang, et al.
Published: (2022-10-01) -
140 anos da Casa de Camões
by: Joaquim Costa Pereira Pinto
Published: (1977-06-01) -
Polydopamine-coated biomimetic bone scaffolds loaded with exosomes promote osteogenic differentiation of BMSC and bone regeneration
by: Yi Zhou, et al.
Published: (2023-06-01)