Analysis of gene expression profiles and protein-protein interaction networks in multiple tissues of systemic sclerosis

Analysis of gene expression profiles and protein-protein interaction networks in multiple tissues of systemic sclerosis

Abstract Background Systemic sclerosis (SSc), a multi-organ disorder, is characterized by vascular abnormalities, dysregulation of the immune system, and fibrosis. The mechanisms underlying tissue pathology in SSc have not been entirely understood. This study intended to investigate the common and t...

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Bibliographic Details
Main Authors: Elham Karimizadeh, Ali Sharifi-Zarchi, Hassan Nikaein, Seyedehsaba Salehi, Bahar Salamatian, Naser Elmi, Farhad Gharibdoost, Mahdi Mahmoudi
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Medical Genomics
Subjects:
Systemic sclerosis
Functional analysis
Common pathway
Integrative gene expression analysis
Online Access:https://doi.org/10.1186/s12920-019-0632-2

Internet

https://doi.org/10.1186/s12920-019-0632-2

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