Group A streptococcal collagen-like protein 1 restricts tumor growth in murine pancreatic adenocarcinoma and inhibits cancer-promoting neutrophil extracellular traps

Group A streptococcal collagen-like protein 1 restricts tumor growth in murine pancreatic adenocarcinoma and inhibits cancer-promoting neutrophil extracellular traps

IntroductionPancreatic ductal adenocarcinoma (PDAC) is a lethal cancer associated with an immunosuppressive environment. Neutrophil extracellular traps (NETs) were initially described in the context of infection but have more recently been implicated in contributing to the tolerogenic immune respons...

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Bibliographic Details
Main Authors: Emily A. Henderson, Abby Ivey, Soo Jeon Choi, Stell Santiago, Dudley McNitt, Tracy W. Liu, Slawomir Lukomski, Brian A. Boone
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
pancreatic cancer
neutrophil extracellular traps
bacteriotherapy
group A Streptococcus
myeloperoxidase
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1363962/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1363962/full

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