Region-based association analysis of human quantitative traits in related individuals.

Region-based association analysis of human quantitative traits in related individuals.

Regional-based association analysis instead of individual testing of each SNP was introduced in genome-wide association studies to increase the power of gene mapping, especially for rare genetic variants. For regional association tests, the kernel machine-based regression approach was recently propo...

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Bibliographic Details
Main Authors: Nadezhda M Belonogova, Gulnara R Svishcheva, Cornelia M van Duijn, Yurii S Aulchenko, Tatiana I Axenovich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3684601?pdf=render

Internet

http://europepmc.org/articles/PMC3684601?pdf=render

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