Identification of dendritic cell precursor from the CD11c+ cells expressing high levels of MHC class II molecules in the culture of bone marrow with FLT3 ligand

Dendritic cells (DCs) are readily generated from the culture of mouse bone marrow (BM) treated with either granulocyte macrophage-colony stimulating factor (GM-CSF) or FMS-like tyrosine kinase 3 ligand (FLT3L). CD11c+MHCII+ or CD11c+MHCIIhi cells are routinely isolated from those BM cultures and gen...

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Main Authors: Hyunju In, Ji Soo Park, Hyun Soo Shin, Seul Hye Ryu, Moah Sohn, Wanho Choi, Sejung Park, Soomin Hwang, Jeyun Park, Lihua Che, Tae-Gyun Kim, Min Kyung Chu, Hye Young Na, Chae Gyu Park
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1179981/full