Luteolin-β-CD-MOF prevents against acetaminophen-mediated liver damage by controlling ferroptosis through GSH/GPX4/SLC7A11 signal axis

Luteolin-β-CD-MOF prevents against acetaminophen-mediated liver damage by controlling ferroptosis through GSH/GPX4/SLC7A11 signal axis

Excess acetaminophen can result in hepatotoxicity, while luteolin has the anti-liver injury property. However, the low water solubility reduces its pharmacological performance. Luteolin-β-Cyclodextrin-Metal-Organic-Framework (Luteolin-β-CD-MOF) is an alternative with more water-soluble activity of l...

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Bibliographic Details
Main Authors: Dan Yang, Min Zhao, Yumeng Zhang, Miao Wang, Chunjie Zhao
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Journal of Functional Foods
Subjects:
Luteolin
Liver injury
Ferroptosis
Bile acid metabolism
Glutathione metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624001403

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http://www.sciencedirect.com/science/article/pii/S1756464624001403

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