Macromutations Yielding Karyotype Alterations (and the Process(es) behind Them) Are the Favored Route of Carcinogenesis and Speciation

It is argued that carcinogenesis and speciation are evolutionary events which are based on changes in the ‘karyotypic code’ through a phase of ‘genome instability’, followed by a bottleneck of selection for the viability and adaptability of the initial cells. Genomic (i.e., chromosomal) instability...

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Bibliographic Details
Main Author: Ingo Schubert
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/3/554