Role of HNF6 in liver homeostasis and pathophysiology

Abstract Background Hepatocyte nuclear factor 6 (HNF6), a member of the HNF family, contains single cleft and homologous domains, which form a DNA-binding region that targets the promoter regions of genes that bind to liver-specific genes and regulate their expression. Furthermore, HNF6 is highly ex...

ver descrição completa

Detalhes bibliográficos
Main Authors: Miaomiao Tian, Weizhen Gao, Shujun Ma, Huiling Cao, Yu Zhang, Fuxiang An, Jianni Qi, Zhen Yang
Formato: Artigo
Idioma:English
Publicado em: BMC 2025-02-01
Colecção:Molecular Medicine
Assuntos:
Acesso em linha:https://doi.org/10.1186/s10020-025-01105-9