Robust analyzes for longitudinal clinical trials with missing and non-normal continuous outcomes

Missing data is unavoidable in longitudinal clinical trials, and outcomes are not always normally distributed. In the presence of outliers or heavy-tailed distributions, the conventional multiple imputation with the mixed model with repeated measures analysis of the average treatment effect (ATE) ba...

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Bibliographic Details
Main Authors: Siyi Liu, Yilong Zhang, Gregory T. Golm, Guanghan (Frank) Liu, Shu Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-09-01
Series:Statistical Theory and Related Fields
Subjects:
Online Access:http://dx.doi.org/10.1080/24754269.2023.2261351