Robust analyzes for longitudinal clinical trials with missing and non-normal continuous outcomes
Missing data is unavoidable in longitudinal clinical trials, and outcomes are not always normally distributed. In the presence of outliers or heavy-tailed distributions, the conventional multiple imputation with the mixed model with repeated measures analysis of the average treatment effect (ATE) ba...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2023-09-01
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Series: | Statistical Theory and Related Fields |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/24754269.2023.2261351 |