Nuclear tristetraprolin acts as a corepressor of multiple steroid nuclear receptors in breast cancer cells

Nuclear tristetraprolin acts as a corepressor of multiple steroid nuclear receptors in breast cancer cells

Tristetraprolin (TTP) is a 34-kDa, zinc finger-containing factor that in mammalian cells acts as a tumor suppressor protein through two different mechanisms. In the cytoplasm TTP promotes the decay of hundreds of mRNAs encoding cell factors involved in inflammation, tissue invasion, and metastasis....

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Bibliographic Details
Main Authors: Tonatiuh Barrios-García, Vania Gómez-Romero, Ángeles Tecalco-Cruz, Viviana Valadéz-Graham, Alfonso León-Del-Río
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Tristetraprolin
Nuclear receptor
Corepressor
Transactivation activity
Estrogen
Progesterone
Glucocorticoid
Androgen
Breast cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S221442691630009X

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http://www.sciencedirect.com/science/article/pii/S221442691630009X

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