Impaired desensitization of a human polymorphic α<sub>2B</sub>-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells
<p>Abstract</p> <p>Background</p> <p>α<sub>2</sub>-adrenergic receptors (ARs) mediate many cellular actions of epinephrine and norepinephrine and inhibit their secretion from adrenal chromaffin cells. Like many other G-protein coupled receptors (GPCRs), they...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-02-01
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| Series: | Cell Communication and Signaling |
| Online Access: | http://www.biosignaling.com/content/9/1/5 |