Targeting and regulation of autophagy in hepatocellular carcinoma: revisiting the molecular interactions and mechanisms for new therapy approaches

Targeting and regulation of autophagy in hepatocellular carcinoma: revisiting the molecular interactions and mechanisms for new therapy approaches

Abstract Autophagy is an evolutionarily conserved process that plays a role in regulating homeostasis under physiological conditions. However, dysregulation of autophagy is observed in the development of human diseases, especially cancer. Autophagy has reciprocal functions in cancer and may be respo...

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Main Authors: Mehrdad Hashemi, Niloufar Nadafzadeh, Mohammad Hassan Imani, Romina Rajabi, Setayesh Ziaolhagh, Seyedeh Delaram Bayanzadeh, Raheleh Norouzi, Reihaneh Rafiei, Zeinab Khazaei Koohpar, Behnaz Raei, Mohammad Arad Zandieh, Shokooh Salimimoghadam, Maliheh Entezari, Afshin Taheriazam, Athanasios Alexiou, Marios Papadakis, Shing Cheng Tan
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cell Communication and Signaling
Subjects:
Hepatocellular carcinoma
Autophagy
Chemoresistance
Metastasis
Stemness
Online Access:https://doi.org/10.1186/s12964-023-01053-z

Internet

https://doi.org/10.1186/s12964-023-01053-z

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