Glycogen Synthase Kinase 3β Is a Key Regulator in the Inhibitory Effects of Accumbal Cocaine- and Amphetamine-Regulated Transcript Peptide 55–102 on Amphetamine-Induced Locomotor Activity

Glycogen Synthase Kinase 3β Is a Key Regulator in the Inhibitory Effects of Accumbal Cocaine- and Amphetamine-Regulated Transcript Peptide 55–102 on Amphetamine-Induced Locomotor Activity

Microinjection of cocaine- and amphetamine-regulated transcript (CART) peptide 55–102 into the nucleus accumbens (NAcc) core significantly attenuates psychostimulant-induced locomotor activity. However, the molecular mechanism remains poorly understood. We examined the phosphorylation levels of Akt,...

Full description

Bibliographic Details
Main Authors: Bo Ram Cho, Wha Young Kim, Ju Kyong Jang, Jung Won Lee, Jeong-Hoon Kim
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
amphetamine
nucleus accumbens
CART
GSK3β
locomotor activity
Online Access:https://www.mdpi.com/1422-0067/23/24/15633

Internet

https://www.mdpi.com/1422-0067/23/24/15633

Similar Items