Bacteriophage Cocktail and Microcin-Producing Probiotic Escherichia coli Protect Mice Against Gut Colonization With Multidrug-Resistant Escherichia coli Sequence Type 131

Bacteriophage Cocktail and Microcin-Producing Probiotic Escherichia coli Protect Mice Against Gut Colonization With Multidrug-Resistant Escherichia coli Sequence Type 131

Non-antibiotic measures are needed to reduce the rate of infections due to multidrug-resistant organisms (MDROs), including by eliminating the commensal reservoir that underlies such strains’ dissemination and leads to recurrent infections. Here, we tested a cocktail of pre-selected bacteriophages a...

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Bibliographic Details
Main Authors: Stephen B. Porter, Brian D. Johnston, Dagmara Kisiela, Connie Clabots, Evgeni V. Sokurenko, James R. Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
intestinal colonization
bacteriophage
probiotic
multidrug resistance
microcin
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.887799/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.887799/full

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