7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs

7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs

Abstract Background Knowledge of the three-dimensional structure of the genome is necessary to understand how gene expression is regulated. Recent experimental techniques such as Hi-C or ChIA-PET measure long-range chromatin interactions genome-wide but are experimentally elaborate, have limited res...

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Bibliographic Details
Main Authors: Jonas Ibn-Salem, Miguel A. Andrade-Navarro
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Genomics
Subjects:
Chromatin interactions
Three-dimensional genome architecture
Transcription factors
ChIP-seq
3C
4C
Online Access:http://link.springer.com/article/10.1186/s12864-019-6088-0

Internet

http://link.springer.com/article/10.1186/s12864-019-6088-0

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