Polynucleotide phosphorylase: Not merely an RNase but a pivotal post-transcriptional regulator.

Almost 60 years ago, Severo Ochoa was awarded the Nobel Prize in Physiology or Medicine for his discovery of the enzymatic synthesis of RNA by polynucleotide phosphorylase (PNPase). Although this discovery provided an important tool for deciphering the genetic code, subsequent work revealed that the...

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Bibliographic Details
Main Authors: Todd A Cameron, Lisa M Matz, Nicholas R De Lay
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6181284?pdf=render