Mucosal-Associated Invariant T Cells Develop an Innate-Like Transcriptomic Program in Anti-mycobacterial Responses

Mucosal-Associated Invariant T Cells Develop an Innate-Like Transcriptomic Program in Anti-mycobacterial Responses

Conventional T cells exhibit a delayed response to the initial priming of peptide antigens presented by major histocompatibility complex (MHC) proteins. Unlike conventional T cells, mucosal-associated invariant T (MAIT) cells quickly respond to non-peptidic metabolite antigens presented by MHC-relat...

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Bibliographic Details
Main Authors: Manju Sharma, Shuangmin Zhang, Liang Niu, David M. Lewinsohn, Xiang Zhang, Shouxiong Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
mucosal-associated invariant T (MAIT) cells
transcriptome
MHC-related protein 1 (MR1)
Mycobacterium tuberculosis
innate-like activation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01136/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.01136/full

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