Visceral Adipose Tissue E2F1-miRNA206/210 Pathway Associates with Type 2 Diabetes in Humans with Extreme Obesity

Visceral Adipose Tissue E2F1-miRNA206/210 Pathway Associates with Type 2 Diabetes in Humans with Extreme Obesity

<i>Objective:</i> Up-regulated expression of transcription-factor E2F1 in human visceral adipose tissue (VAT) characterizes a dysmetabolic obesity sub-phenotype. An E2F1-miRNA network has been described in multiple cancers. Here we investigated whether elevated VAT-E2F1 in obesity is ass...

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Bibliographic Details
Main Authors: Nitzan Maixner, Yulia Haim, Matthias Blüher, Vered Chalifa-Caspi, Isana Veksler-Lublinsky, Nataly Makarenkov, Uri Yoel, Nava Bashan, Idit F. Liberty, Ivan Kukeev, Oleg Dukhno, Dan Levy, Assaf Rudich
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
obesity
E2F1
miR-206
miR-210-5p
dys-glycemia
Online Access:https://www.mdpi.com/2073-4409/11/19/3046

Internet

https://www.mdpi.com/2073-4409/11/19/3046

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