Behavioral and neuroanatomical abnormalities in pleiotrophin knockout mice.

Pleiotrophin (PTN) is an extracellular matrix-associated protein with neurotrophic and neuroprotective effects that is involved in a variety of neurodevelopmental processes. Data regarding the cognitive-behavioral and neuroanatomical phenotype of pleiotrophin knockout (KO) mice is limited. The purpo...

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Bibliographic Details
Main Authors: Jason W Krellman, Henry H Ruiz, Veronica A Marciano, Bracha Mondrow, Susan D Croll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4085064?pdf=render