Targeting hepatic oxidative stress rescues bone loss in liver fibrosis

Targeting hepatic oxidative stress rescues bone loss in liver fibrosis

Objective: Chronic liver diseases often involve metabolic damage to the skeletal system. The underlying mechanism of bone loss in chronic liver diseases remains unclear, and appropriate therapeutic options, except for orthotopic liver transplantation, have proved insufficient for these patients. Thi...

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Bibliographic Details
Main Authors: Soichiro Sonoda, Sara Murata, Haruyoshi Yamaza, Ratih Yuniartha, Junko Fujiyoshi, Koichiro Yoshimaru, Toshiharu Matsuura, Yoshinao Oda, Shouichi Ohga, Tasturo Tajiri, Tomoaki Taguchi, Takayoshi Yamaza
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Molecular Metabolism
Subjects:
Chronic liver diseases
Hepatic osteodystrophy
Reactive oxidative species
Stanniocalcin 1
Interleukin 17
Neutrophils
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822001685

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http://www.sciencedirect.com/science/article/pii/S2212877822001685

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