Anxiety in synucleinopathies: neuronal circuitry, underlying pathomechanisms and current therapeutic strategies

Abstract Synucleinopathies are neurodegenerative disorders characterized by alpha-synuclein (αSyn) accumulation in neurons or glial cells, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). αSyn-related pathology plays a critical role in the patho...

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Bibliographic Details
Main Authors: Thuy Thi Lai, Birthe Gericke, Malte Feja, Michael Conoscenti, Moriel Zelikowsky, Franziska Richter
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00547-4